NOT saying the .22 LR is an ideal self defence calibre, but showing performance.
Anybody who has hunted farm predators or used a .22 to slaughter livestock knows this stuff.
22LR subsonic through 1/2" pine at 400 yards, (equivalent to human skull).
https://www.youtube.com/watch?v=OUM1r_444CY
22LR 11" penetration of ballistic gel block @ 300 yards
https://www.youtube.com/watch?v=-DzLQGv-w5M
22LR handgun through 4 interior house doors
https://www.youtube.com/watch?v=wzUpQe63mpc
22LR through 11 layers dry gypsum wall board.
https://www.youtube.com/watch?v=1pSVn7ozXTQ
22LR through vehicle windscreen + gel block rapid fire
https://www.youtube.com/watch?v=yKFvrqCG118
22LR through cowbone + 13" wetpacked paper
https://www.youtube.com/watch?v=I8ANIBno8CQ
22LR though both sides deer skull
https://www.youtube.com/watch?v=VW2C3exp0R4
Ruger 10/.22 plinking 400 yards.
https://www.youtube.com/watch?v=tZuIvKeUAgM
22LR plinking 700 yards.
https://www.youtube.com/watch?v=lQEbJhcx4os
22LR on live domestic hog
https://www.youtube.com/watch?v=IjzpLN46nOo